If recent discoveries are true that the COVID virus isn't a pulmonary disease but presents more like altitude type sickness condition with very low oxygen levels in the blood then we should be focusing on alkalizing our body and naturally boosting the body's ability to retain more oxygen.

Here are some natural protocols to enhance oxygen levels in the blood.

1. Exercise. Fast walking so you break a sweat, up to 1 hr. a day.

2. Alkaline diet. You want to refer to this link for a thorough list.
https://www.acidalkalinediet.com/list-of-alkaline-foods
Print out the list of beneficial foods that alkalize the body. Alkaline blood holds 20% more oxygen. An alkaline diet is a lifestyle, a preventative approach to food therapy that can prevent most modern illnesses.

3. Abdominal breathwork increases the oxygen levels in the blood, one of my favorite practices, the benefits are enormous.
https://www.youtube.com/watch?v=8UURgA8Rf7E

4. Stay hydrated with water. Half your body weight in ounces should be sipped throughout the day. Sipping water not gulping.

5. Antioxidant therapy. The master antioxidant is Glutathione. It is an antioxidant fount in plants, animals, fungi, and some bacteria and archaea. Glutathione is capable of preventing damage to important cellular components caused by reactive oxygen species such as free radicals, peroxides, lipid peroxides, and heavy metals. Since I am a big proponent to consuming foods rich in antioxidants, I take it in a powder drink. Ask me for the details. For those who want to maximize release
of glutathione, coffee enemas stimulate bile flow and the production of glutathione.
https://www.medicalnewstoday.com/articles/325873
Other very significant antioxidants are alpha lipoic acid, and CoQ10.

6. Iron is an essential mineral used to transport oxygen to all parts of the body. Iron from natural food sources, like the ones listed in this link are considered essential. https://www.myfooddata.com/articles/food-sources-of-iron.php

7. Chlorophyll intake results in increased red blood cell count. This is highly beneficial for the organism, since red blood cells are responsible with carrying oxygen from the lungs to the rest of the body.
https://www.lifejacks.com/5-chlorophyll-rich-foods-eat-often/

8. Vitamin B12 and folate rich foods.
https://www.healthline.com/nutrition/vitamin-b12-foods
https://www.healthline.com/nutrition/foods-high-in-folate-folic-acid

9. Vitamin A rich foods.
https://www.healthline.com/nutrition/foods-high-in-vitamin-a

10. Baking soda. Dilute ½ tsp. to 4 oz. water, drink twice a day.

11. Apple cider vinegar. Dilute 1 tbsp. to 2 oz. water, drink twice a day.

12. Intermittent fasting.
https://www.healthline.com/nutrition/intermittent-fasting-guide

13. Improve circulation of blood with massage, tuina, taichi, qigong and acupuncture.

14. Manage stress with meditation, yoga, and other harmonizing activities.

15. Quality sleep. According to Chinese Medicine, two organ systems are responsible for detoxifying the blood, building blood, and filtering waste from 11pm to 5am. We need quality sleep for this process to occur.
​
16. Did you know that laughter increases oxygen levels in the body? So let’s laugh more, much more!

According to CDC, there is currently no vaccine to prevent coronavirus disease 2019 (COVID-19). The best way to prevent illness is to avoid being exposed to this virus. However, as a reminder, CDC always recommends everyday preventive actions to help prevent the spread of respiratory diseases, including:

• Avoid close contact with people who are sick.
• Avoid touching your eyes, nose, and mouth.
• Stay home when you are sick.
• Cover your cough or sneeze with a tissue, then throw the tissue in the trash.
• Clean and disinfect frequently touched objects and surfaces using a regular household cleaning spray or wipe.
• Follow CDC’s recommendations for using a facemask.
  • CDC does not recommend that people who are well wear a facemask to protect themselves from respiratory diseases, including COVID-19.
  • Facemasks should be used by people who show symptoms of COVID-19 to help prevent the spread of the disease to  others. 
• Wash your hands often with soap and water for at least 20 seconds, especially after going to the bathroom; before eating; and after blowing your nose, coughing, or sneezing.
  • If soap and water are not readily available, use an alcohol-based hand sanitizer with at least 60% alcohol. Always wash hands with soap and water if hands are visibly dirty. 
• Do your best not to live in fear or anxiety about the situation.  Yes, it is a serious matter that requires our attention.  However, it is important to note that when we get trapped in a fear response our immune systems shut down in favor of survival mechanisms, which actually further heighten our anxiety! Be wise and discerning about your lifestyle practices and choices, and trust you are doing what you can to keep yourself and your family safe.
• Fresh air is vital to healthy immunity - make a point of getting outside, daily.  Even as little as 10 to 15 minutes three times throughout the day will benefit you.
• Rest!  Get plenty of sleep and rest.
• Take some time off, perhaps use this time for a personal at-home retreat where you just enjoy some time spent away from work, extra-curricular activities and the hustle and bustle of life.  Walks in nature, healthy dinners together with your family, board games, curling up with a good book and limiting your social contact are all enriching ways to protect yourself from community transmission.
• Increase your consumption of anti-oxidant and nutrient-dense infection-fighting foods like: organic blueberries, raspberries, spinach, sprouts, garlic, onions, ginger, parsley, cilantro, spirulina, celery juice, bone broth and fermented foods and beverages.
• Drink lots of water. Drinking good quality water and herbal teas, staying hydrated, is one of the best things you can do to flush out toxins from your body and help support the immune system.
• Keep your immune system strong by reducing your sugar intake and eating a balanced diet.  Avoid eating processed sugars. Sugar weakens the immune system and makes it less able to deal with viruses and bacteria.  Be sure to read food labels carefully and to limit the amount of sugar you eat.

More helpful tips
#1  Chop into a mason jar fresh ginger, turmeric, add a little bit of cayenne and black pepper and steep in honey for 2 weeks. Refrigerate this solution and dilute 2 tbsp. to one cup hot water 1-2x day.
#2  Drink Hot Liquids. Hot ginger, lemon, honey tea and a clear bone broth. Include 1 tbsp. of apple cider vinegar 2-3x day.
#3  Healthy eating prevents disease. Unhealthy processed foods packed with preservatives and added sugar unnecessarily reduce the body’s immune system exposing them to potential illness. 
#4  Avoid inflammatory foods like sugar, carbs, dairy, alcohol, caffeine and animal fats. A plant based diet is recommended.
#6  Staying in good shape is also one of the best ways to keep the immune strong so that if you do get sick, your body will do a better job at healing faster. 
#7  If you are a smoker, your lungs are vulnerable. This virus affects the lungs, talk to your acupuncturist about quitting smoking.
#8  The immune system is linked to gut health. Consuming fermented foods, enzymes and probiotics is essential to boost immune function.
#9  There are effective Chinese and Western herbal formulas that should be used as a preventative. 
#10  Your mindset is super important, your thought pattern can create your reality. Science is proving this. If you are constantly watching negative news and think "I am going to get the flu", then you will attract that outcome. 
​
Talk to your acupuncturist about herbs to address your underlying deficiencies. When you address strengthening core weaknesses then you are supporting total body wellness and hence your immune system benefits.

The above information was partially adopted from CDC website, Inno-vita, WebMD, AAC
For educational purposes only. This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

I have been a huge enthusiast of bone broth especially when cooked with Chinese herbs to enhance immune and endocrine function, strengthen connective tissue, improve digestive function, strengthen blood, qi and bones.
ingredients: ren shen, dong quai, huang qi, hong zao, lycii berry, chuan xiong, and dang shen.
Soon to come, I will be making ginseng (with other essential herbs) bone broth for order. Will be available in quart sizes.

A staple of the human diet for thousands of years, bone broth is enjoying a resurgence of interest due to its powerful health benefits. Bone broth is easy to incorporate in your diet as a base for soups, stews and legumes. Follow our recipe below to make your own fortifying and replenishing broth.

Top 5 Reasons to Eat Bone Broth:
1. Nourish Your Gut
Bone broth is full of gelatin and collagen, which soothes the intestinal tract and helps heal leaky gut, aka intestinal permeability. With stress, diet, alcohol, caffeine and NSAIDS wreaking havoc on our intestines, anything and everything we can do to help repair the gut is beneficial, as a healthy intestinal tract is essential to overall good health.

2. Boost Your Immune System
Yes, Grandma was right about chicken soup. A traditional folk remedy for colds and flus, bone broth provides a rich array of nutrients (especially gelatin) which support your immune system. Cysteine, an amino acid found in chicken, helps to thin mucus so it can be expelled more easily. When fighting a cold, make a chicken broth with added spices or peppers to make it spicy to help keep the mucus moving.

3. Increase Bio-available Minerals
As a result of soil degradation, the mineral content of our foods is reduced, and many of us have compromised absorption due to poor gut health. Yet minerals are critical to so many bodily functions and impact everything from our bones to our mood and our sleep. Supplying calcium, magnesium, potassium, silicon, sulfur and phosphorous, bone broth provides an excellent means of boosting your mineral intake. 

4. Promote Healthy Skin
A rich source of skin-supporting amino acids glycine and proline, along with collagen, the ultimate skin food, bone broth can improve skin elasticity and fight wrinkles.

5. Reduce Inflammation
Glucosamine, chondroitin, collagen, and gelatin support your joints, bones, and reduce inflammation throughout your body.

How to Make Bone Broth
Broth is forgiving so exact measurements are not required for success. The essential ingredients are simply bones, water and vinegar, which draws the minerals out from the bones. Vegetables (carrots, garlic, onion), sea salt and herbs improve the flavor and can be added towards the end of the cooking time, if desired.

Ingredients:

• 2 – 4 lbs bones – from poultry, fish, shellfish, beef or lamb (pastured, organic, and grass-fed)
• 1 gallon water or enough to cover bones (approx. 2 cups of water per 1 pound of bones)
• 3 – 4 tablespoons of apple cider vinegar (or other natural vinegar)  

Pour water and vinegar over raw or cooked bones in a large pot (e.g. the remains of a roasted chicken) and let sit for 30 – 60 minutes. Heat the pot and bring the water to a boil. Skim any scum that rises to the top. Reduce heat and allow the broth to simmer gently. Cook on low for at least 6 hours or overnight, to extract the most gelatin and nutrients from the bones. Use your slow cooker if you have one. After several hours of barely simmering, remove from heat and strain through a fine mesh sieve, strainer or cheesecloth. Use as a base for any type of soup, or drink one cup a day for a health-promoting tonic.


Written by Be Well Health Coach Laura Kraber.
For educational purposes only. This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Impressive new research is emerging every day regarding the role of the microbiome of the digestive tract lining. The microbiome refers to the healthful bacteria, or ‘good germs’ that line our digestive tracts. The digestive tract itself is a center point of the nervous system, hormonal system and immune system. It is responsible for the balance of the our molecules of emotion, the neurotransmitters, and as a result is an important player for best mood. And good bacteria is an important part of healthy digestion.  Probiotics are known not only to help the digestion, but are key factors in obesity, hormonal balance, healthy kidney function, and much more.

How Do Probiotics Help the Brain?

Medical research is uncovering the mechanism of probiotics in mood. These healthy germs boost mood in two important ways: they generate a particular neurotransmitter called gamma-aminobutyric acid (GABA) and also enhance the brain receptors for GABA as well. Like a warm and gentle blanket for the brain, GABA is calming amino acid, known to calm areas of the brain that are over active in anxiety and panic and in some forms of anxious depression.

Animal studies working with mice showed those mice who ingested probiotics were, in general, more chilled out than the control mice.  The probiotic mice had lower levels of corticosterone in response to stress. Corticosterone is the mouse version of the human stress hormone cortisol. High levels of cortisol are common in anxiety as well as depression.  These mice were fed either the probiotic strain Lactobacillus rhamnosus or a broth without these. The lactobacillus-fed animals showed significantly fewer stress, anxiety and depression-related behaviors than those fed with just broth (Bravo et al., 2011).
Human studies have also corroborated these murine (mouse) findings. A French team learned via a double-blinded, placebo-controlled, randomized parallel group study that giving humans specific strains of Lactobacillus and Bifidobacterium for 30 days yielded beneficial psychological effects including lowered depression, less anger and hostility, anxiety, and better problem solving, compared with the placebo group (Messaoudi et al., 2011). 

Yeast and the Microbiome

While a healthy microbiome will contribute to good mood, an unhealthy one full of Candida albicans (yeast), and all the toxins associated with it, may also contribute to mood disorder. Presence of yeast will alter the ability to absorb nutrients and push hypersensitivity reactions of toxin by-products which translates to inflammation in the body. Inflammation will greatly contribute to depression, anxiety and poor mental function (Rucklidge, 2013).

What You Can Do To Keep Your Microbiome Healthy?

Steps you can take for a healthy microbiome and mood are:

1 – Avoid excess sugary foods: to avoid yeast build up. 

2 – Good Quality Sleep: good sleep is key for the intestinal lining to repair and create a healthy microbiome.

3 – Meditation and Relaxation: Meditation and quality down time is important to keep the body in the ‘rest and digest’ mode instead of stress mode. Stress mode shuts circulation to the gut, which doesn’t allow a healthy microbiome.

4 – Eat Foods with Fiber: Good fiber helps feed the good bacteria and keeps them healthy. Vegetables, fruits, psyllium, flax, inulin and other fibers also help keep good flora and proper balance of short chain fatty acids in the intestines. 

5 – Eat Probiotic Foods: While the French study mentioned above used a supplement, there are also many wonderful natural foods full of probiotics. In my opinion, foods, over supplements, are always the best way to go for long term health. These include natto (a traditional Japanese fermented food), kim chi (Korean style cabbage), sauerkraut, yogurt, kefir, tempeh, fermented milk (like buttermilk), miso, and non-baked cheeses (like aged cheese). Homemade sauerkraut is better than store bought, for the store bought stuff is pasteurized, which kills some of the good probiotics.

6 – Consider a probiotic supplement: For patients with health issues, sometimes it makes sense to use a supplement along with foods. A good quality supplement should contain with Lactobacillus and bifidus bacteria. There are a number of good ones on the market and some that are poorly made, so if you choose to take a supplement, make sure the manufacturer is of the highest quality in terms of raw materials, culturing techniques, and quality control. My clinic uses Restoraflora, which contains about 4 billion bacteria per capsule. If you purchase one in the store, find a refrigerated version that doesn't have any binders, fillers, milk products, or corn.

reference: https://www.psychologytoday.com/blog/inner-source/201411/the-gut-microbiome-anxiety-and-depression-6-steps-take

For educational purposes only. This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

Adversity in childhood can create long-lasting scars, damaging our cells and our DNA, and making us sick as adults, by Donna Jackson Nakazawa
Donna is a science journalist whose work has appeared in Psychology Today, The Washington Post and Glamour, among others. Her latest book is Childhood Disrupted (2015). She lives in Maryland.

If you saw Laura walking down the New York City street where she lives today, you’d see a well-dressed 46-year-old woman with auburn hair and green eyes, who exudes a sense of ‘I matter here.’ She looks entirely in charge of her life, but behind Laura’s confident demeanour lies a history of trauma: a bipolar mother who vacillated between braiding her daughter’s hair and peppering her with insults, and a father who moved out-of-state with his wife-to-be when Laura was 15 years old.
She recalls a family trip to the Grand Canyon when she was 10. In a photo taken that day, Laura and her parents sit on a bench, sporting tourist whites. ‘Anyone looking at us would have assumed that we were a normal, loving family.’ But as they put on fake smiles for the camera, Laura’s mother suddenly pinched her daughter’s midriff and told her to stop ‘staring off into space’. A second pinch: ‘No wonder you’re turning into a butterball, you ate so much cheesecake last night you’re hanging over your shorts!’ If you look hard at Laura’s face in the photograph, you can see that she’s not squinting at the Arizona sun, but holding back tears.
After her father left the family, he sent cards and money, but called less and less. Meanwhile, her mother’s untreated bipolar disorder worsened. Sometimes, Laura says: ‘My mom would go on a vitriolic diatribe about my dad until spittle foamed on her chin. I’d stand there, trying not to hear her as she went on and on, my whole body shaking inside.’ Laura never invited friends over, for fear they’d find out her secret: her mom ‘wasn’t like other moms’.
Some 30 years later, Laura says: ‘In many ways, no matter where I go or what I do, I’m still in my mother’s house.’ Today, ‘If a car swerves into my lane, a grocery store clerk is rude, my husband and I argue, or my boss calls me in to talk over a problem, I feel something flip over inside. It’s like there’s a match standing inside too near a flame, and with the smallest breeze, it ignites.’
To see Laura, you’d never know that she is ‘always shaking a little, only invisibly, deep down in my cells’.
Her sense that something is wrong inside is mirrored by her physical health. During a routine exam, Laura’s doctor discovered that Laura was suffering from dilated cardiomyopathy and would require a cardioverter defibrillator to keep her heart pumping. The two-inch scar from her surgery only hints at the more severe scars she hides from her childhood.
For as long as John can remember, he says, his parents’ marriage was deeply troubled, as was his relationship with his father. ‘I consider myself to have been raised by my mom and her mom. I longed to feel a deeper connection with my dad, but it just wasn’t there. He couldn’t extend himself in that way.’ John’s poor relationship with his father was due, in large part, to his father’s reactivity and need for control. For instance, if John’s father said that the capital of New York was New York City, there was just no use telling him that it was Albany.
As John got older, it seemed wrong to him that his father ‘was constantly pointing out all the mistakes that my brother and I made, without acknowledging any of his own’. His father relentlessly criticised his mother, who was ‘kinder and more confident’. Aged 12, John began to interject himself into the fights between his parents. He remembers one Christmas Eve, when he found his father with his hands around his mother’s neck and had to separate them. ‘I was always trying to be the adult between them,’ John says.
John is now a boyish 40, with warm hazel eyes and a wide, affable grin. But beneath his easy, open demeanour, he struggles with an array of chronic illnesses. By the time he was 33, his blood pressure was shockingly high; he began to experience bouts of stabbing stomach pain and diarrhoea and often had blood in his stool; he struggled from headaches almost daily. By 34, he’d developed chronic fatigue, and was so wiped out that he sometimes struggled to make it through an entire workday.
John’s relationships, like his body, were never completely healthy. He ended a year‑long romance with a woman he deeply loved because he felt riddled with anxiety around her normal, ‘happy family’. He just didn’t know how to fit in. ‘She wanted to help,’ he says, ‘but instead of telling her how insecure I was around her, I told her I wasn’t in love with her.’ Bleeding from his inflamed intestines, exhausted by chronic fatigue, debilitated and distracted by pounding headaches, often struggling with work, and unable to feel comfortable in a relationship, John was stuck in a universe of pain and solitude, and he couldn’t get out.

Laura’s and John’s life stories illustrate the physical price we can pay, as adults, for trauma that took place 10, 20, even 30 years ago. New findings in neuroscience, psychology and immunology tell us that the adversity we face during childhood has farther-reaching consequences than we might ever have imagined. Today, in labs across the country, neuroscientists are peering into the once-inscrutable brain-body connection, and breaking down, on a biochemical level, exactly how the stress we experience during childhood and adolescence catches up with us when we are adults, altering our bodies, our cells, and even our DNA.
Emotional stress in adult life affects us on a physical level in quantifiable, life-altering ways. We all know that when we are stressed, chemicals and hormones can flush our body and increase levels of inflammation. That’s why stressful events in adult life are correlated with the likelihood of getting a cold or having a heart attack.
But when children or teens face adversity and especially unpredictable stressors, they are left with deeper, longer‑lasting scars. When the young brain is thrust into stressful situations over and over again without warning, and stress hormones are repeatedly ramped up, small chemical markers, known as methyl groups, adhere to specific genes that regulate the activity of stress‑hormone receptors in the brain. These epigenetic changes hamper the body’s ability to turn off the stress response. In ideal circumstances, a child learns to respond to stress, and recover from it, learning resilience. But kids who’ve faced chronic, unpredictable stress undergo biological changes that cause their inflammatory stress response to stay activated.
Joan Kaufman, director of the Child and Adolescent Research and Education (CARE) programme at the Yale School of Medicine, recently analysed DNA in the saliva of happy, healthy children, and of children who had been taken from abusive or neglectful parents. The children who’d experienced chronic childhood stress showed epigenetic changes in almost 3,000 sites on their DNA, and on all 23 chromosomes – altering how appropriately they would be able to respond to and rebound from future stressors.
kids who’ve had early adversity have a drip of fight-or-flight hormones turned on every day – it’s as if there is no off switch
Likewise, Seth Pollak, professor of psychology and director of the Child Emotion Research Laboratory at the University of Wisconsin at Madison, uncovered startling genetic changes in children with a history of adversity and trauma. Pollak identified damage to a gene responsible for calming the stress response. This particular gene wasn’t working properly; the kids’ bodies weren’t able to reign in their heightened stress response. ‘A crucial set of brakes are off,’ says Pollak.
Imagine for a moment that your body receives its stress hormones and chemicals through an IV drip that’s turned on high when needed and, when the crisis passes, it’s switched off again. You might think of kids whose brains have undergone epigenetic changes because of early adversity as having an inflammation-promoting drip of fight-or-flight hormones turned on every day – it’s as if there is no off switch.
Experiencing stress in childhood changes your set point of wellbeing for decades to come. In people such as Laura and John, the endocrine and immune systems are churning out a damaging and inflammatory cocktail of stress neurochemicals in response to even small stressors – an unexpected bill, a disagreement with their spouse, a car that swerves in front of them on the highway, a creak on the staircase – for the rest of their lives. They might find themselves overreacting to, and less able to recover from, the inevitable stressors of life. They’re always responding. And all the while, they’re unwittingly marinating in inflammatory chemicals, which sets the stage for full-throttle disease down the road, in the form of autoimmune disease, heart disease, cancer, fibromyalgia, chronic fatigue, fibroid tumours, irritable bowel syndrome, ulcers, migraines and asthma.
Scientists first came to understand the relationship between early chronic stress and later adult disease through the work of a dedicated physician in San Diego and a determined epidemiologist from the Centers for Disease Control and Prevention (CDC) in Atlanta. Together, during the 1980s and ’90s – the years when Laura and John were growing up – these two researchers began a paradigm-shifting public-health investigation known as the Adverse Childhood Experiences (ACE) Study.
In 1985, Vincent J Felitti, chief of a revolutionary preventive care initiative at the Kaiser Permanente Medical Care programme in San Diego, noticed a startling pattern in adult patients at an obesity clinic. A significant number were, with the support of Felitti and his nurses, successfully losing hundreds of pounds a year, a remarkable feat, only to withdraw from the programme despite weight-loss success. Felitti, determined to get to the bottom of the attrition rate, conducted face-to-face interviews with 286 patients. It turned out there was a common denominator. Many confided that they had suffered some sort of trauma, often sexual abuse, in their childhoods. To these patients, eating was a solution, not a problem: it soothed the anxiety and depression they had harboured for decades; their weight served as a shield against undesired attention, and they didn’t want to let it go.
Felitti’s interviews gave him a new way of looking at human health and wellbeing that other physicians just weren’t seeing. He presented his findings at a national obesity conference, arguing that ‘our intractable public health problems’ had root causes hidden ‘by shame, by secrecy, and by social taboos against exploring certain areas of life experience’. Felitti’s peers were quick to blast him. One even stood up in the audience and accused Felitti of offering ‘excuses’ for patients’ ‘failed lives’. Felitti, however, remained unfazed; he felt sure that he had stumbled upon a piece of information that would hold enormous import for the field of medicine.
After a colleague who attended that same conference suggested that he design a study with thousands of patients who suffered from a wide variety of diseases, not just obesity, Felitti joined forces with Robert Anda, a medical epidemiologist at the CDC who had, at the time, been researching the relationship between coronary heart disease and depression. Felitti and Anda took advantage of Kaiser Permanente’s vast patient cohort to set up a national epidemiology laboratory. Of the 26,000 patients they invited to take part in their study, more than 17,000 agreed.
Anda and Felitti surveyed these 17,000 individuals on about 10 types of adversity, or adverse childhood experiences (ACEs), probing into patients’ childhood and adolescent histories. Questions included: ‘Was a biological parent ever lost to you through divorce, abandonment or other reason?’; ‘Did a parent or other adult in the household often swear at you, insult you, put you down or humiliate you?’; and ‘Was a household member depressed or mentally ill?’ Other questions looked at types of family dysfunction that included growing up with a parent who was an alcoholic or addicted to other substances; being physically or emotionally neglected; being sexually or physically abused; witnessing domestic violence; having a family member who was sent to prison; feeling that there was no one to provide protection; and feeling that one’s family didn’t look out for each other. For each category to which a patient responded ‘yes’, one point would be added to her ACE score, so an ACE score of 2 would indicate that she had suffered two adverse childhood experiences.
To be clear, the patients Felitti and Anda surveyed were not troubled or disadvantaged; the average patient was 57, and three-quarters had attended college. These were ‘successful’ men and women, mostly white, middle-class, with stable jobs and health benefits. Felitti and Anda expected their number of ‘yes’ answers to be fairly low.
The correlation between having a difficult childhood and facing illness as an adult offered a whole new lens through which we could view human health and disease
When the results came in, Felitti and Anda were shocked: 64 per cent of participants answered ‘yes’ to having encountered at least one category of early adversity, and 87 per cent of those patients also had additional adverse childhood experiences; 40 per cent had suffered two or more ACEs; 12.5 per cent had an ACE score greater than or equal to 4.
Felitti and Anda wanted to find out whether there was a correlation between the number of adverse childhood experiences an individual had faced, and the number and severity of illnesses and disorders she developed as an adult. The correlation proved so powerful that Anda was not only ‘stunned’, but deeply moved.
‘I wept,’ he says. ‘I saw how much people had suffered, and I wept.’
Felitti, too, was deeply affected. ‘Our findings exceeded anything we had conceived. The correlation between having a difficult childhood and facing illness as an adult offered a whole new lens through which we could view human health and disease.’
Here, says Felitti, ‘was the missing piece as to what was causing so much of our unspoken suffering as human beings’.
The number of adverse childhood experiences a patient had suffered could by and large predict the amount of medical care she would require in adulthood: the higher the ACE score, the higher the number of doctor’s appointments she’d had in the past year, and the more unexplained physical symptoms she’d reported.
People with an ACE score of 4 were twice as likely to be diagnosed with cancer than people who hadn’t faced any form of childhood adversity. For each point an individual had, her chance of being hospitalised with an autoimmune disease in adulthood rose 20 per cent. Someone with an ACE score of 4 was 460 per cent more likely to face depression than someone with a score of 0.
An ACE score of 6 or higher shortened an individual’s lifespan by almost 20 years.
Researchers wondered if those who encountered childhood adversity were also more likely to smoke, drink and overeat as a sort of coping strategy, and while that was sometimes the case, unhealthy habits didn’t wholly account for the correlation Felitti and Anda saw between adverse childhood experiences and later illness. For instance, those with ACE scores greater than or equal to 7 who didn’t drink or smoke, weren’t overweight or diabetic, and didn’t have high cholesterol still had a 360 per cent higher risk of heart disease than those with ACE scores of 0.
‘Time,’ says Felitti, ‘does not heal all wounds. One does not “just get over” something – not even 50 years later.’ Instead, he says: ‘Time conceals. And human beings convert traumatic emotional experiences in childhood into organic disease later in life.’
Often, these illnesses can be chronic and lifelong. Autoimmune disease. Heart disease. Chronic bowel disorders. Migraines. Persistent depression. Even today, doctors puzzle over these very conditions: why are they so prevalent; why are some patients more prone to them than others; and why are they so difficult to treat?
The more research that’s done, the more granular details emerge about the profound link between adverse experiences and adult disease. Scientists at Duke University in North Carolina, the University of California, San Francisco, and Brown University in Rhode Island have shown that childhood adversity damages us on a cellular level in ways that prematurely age our cells and affect our longevity. Adults who faced early life stress show greater erosion in what are known as telomeres – protective caps that sit on the ends of DNA strands to keep the DNA healthy and intact. As telomeres erode, we’re more likely to develop disease, and we age faster; as our telomeres age and expire, our cells expire and so, eventually, do we.
Researchers have also seen a correlation between specific types of adverse childhood experiences and a range of diseases. For instance, children whose parents die, or who face emotional or physical abuse, or experience childhood neglect, or witness marital discord between their parents are more likely to develop cardiovascular disease, lung disease, diabetes, headaches, multiple sclerosis and lupus as adults. Facing difficult circumstances in childhood increases six-fold your chances of having myalgic encephalomyelitis (chronic fatigue syndrome) as an adult. Kids who lose a parent have triple the risk of depression in their lifetimes. Children whose parents divorce are twice as likely to suffer a stroke later down the line.
Laura and John’s stories illustrate that the past can tick away inside us for decades like a silent time bomb, until it sets off a cellular message that lets us know the body does not forget its history.
Something that happened to you when you were five or 15 can land you in the hospital 30 years later
John’s ACE score would be a 3: a parent often put him down; he witnessed his mother being harmed; and, clearly, his father suffered from an undiagnosed behaviour health disorder, perhaps narcissism or depression, or both.
Laura had an ACE score of 4.
Laura and John are hardly alone. Two-thirds of American adults are carrying wounds from childhood quietly into adulthood, with little or no idea of the extent to which these wounds affect their daily health and wellbeing. Something that happened to you when you were five or 15 can land you in the hospital 30 years later, whether that something was headline news, or happened quietly, without anyone else knowing it, in the living room of your childhood home.
The adversity a child faces doesn’t have to be severe abuse in order to create deep biophysical changes that can lead to chronic health conditions in adulthood.
‘Our findings showed that the 10 different types of adversity we examined were almost equal in their damage,’ says Felitti. He and Anda found that no single ACE significantly trumped another. This was true even though some types, such as being sexually abused, are far worse in that society regards them as particularly shameful, and others, such as physical abuse, are more overt in their violence.
This makes sense if you think about how the stress response functions on an optimal level. You meet a bear in the woods, and your body floods with adrenaline and cortisol so that you can quickly decide whether to run in the opposite direction or stay and try to frighten the bear. After you deal with the crisis, you recover, your stress hormones abate, and you go home with a great story. For Laura and John, though, that feeling that the bear is still out there, somewhere, circling in the woods, stalking, and might strike again any day, anytime – that feeling never disappears.
There are a lot of bears out there. Chronic parental discord; enduring low-dose humiliation or blame and shame; chronic teasing; the quiet divorce between two secretly seething parents; a parent’s premature exit from a child’s life; the emotional scars of growing up with a hypercritical, unsteady, narcissistic, bipolar, alcoholic, addicted or depressed parent; physical or emotional abuse or neglect: these happen in all too many families. Although the details of individual adverse experiences differ from one home to another and from one neighbourhood to another, they are all precursors to the same organic chemical changes deep in the gray matter of the developing brain.
Every few decades, a groundbreaking psychosocial ‘theory of everything’ helps us to develop a new understanding of why we are the way we are – and how we got that way. In the early 20th century, the psychoanalyst Sigmund Freud transformed the landscape of psychology when he argued that the unconscious rules much of our waking life and dreams. Jungian theory taught, among other ideas, that we tend toward introversion or extroversion, which led the American educationalist Katharine Cook Briggs and her daughter Isabel Briggs Myers to develop a personality indicator. More recently, neuroscientists discovered that age ‘zero to three’ was a critical synaptic window for brain development, giving birth to Head Start and other preschool programmes. The correlation between childhood trauma, brain architecture and adult wellbeing is the newest, and perhaps our most important, psychobiological theory of everything.
Today’s research on adverse childhood experiences revolutionises how we see ourselves, our understanding of how we came to be the way we are, why we love the way we do, how we can better nurture our children, and how we can work to realise our potential.
To date, more than 1,500 studies founded on Felitti and Anda’s hallmark ACE research show that both physical and emotional suffering are rooted in the complex workings of the immune system, the body’s master operating control centre – and what happens to the brain during childhood sets the programming for how our immune systems will respond for the rest of our lives.
The unifying principle of this new theory of everything is this: your emotional biography becomes your physical biology, and together, they write much of the script for how you will live your life. Put another way: your early stories script your biology and your biology scripts the way your life will play out.
Unlike previous theories of everything, though, this one has been mind-bogglingly slow to change how we do medicine, according to Felitti. ‘Very few internists or medical schools are interested in embracing the added responsibility that this understanding imposes on them.’
With the ACE research now available, we might hope that physicians will begin to see patients as a holistic sum of their experiences and embrace the understanding that a stressor from long ago can be a health-risk time bomb that has exploded. Such a medical paradigm, which sees adverse childhood experiences as one of many key factors that can play a role in disease, could save many patients years in the healing process.
But seeing that connection takes a little time. It means asking patients to fill out the ACE questionnaire and delving into that patient’s history for insight into sources of both physical and emotional pain. As health-care budgets have become stretched, physicians spend less time interacting one-on-one with patients in their exam rooms; the average physician schedules patients back-to-back at 15-minute intervals.
Still, the cost of not intervening is far greater – not only in the loss of human health and wellbeing, but also in additional healthcare. According to the CDC, the total lifetime cost of child maltreatment in the US is $124 billion each year. The lifetime healthcare cost for each individual who experiences childhood maltreatment is estimated at $210,012 – comparable to other costly health conditions, such as having a stroke, which has a lifetime estimated cost of $159,846 per person, or type-2 diabetes, which is estimated to cost between $181,000 and $253,000.
Further hindering change is the fact that adult physical medicine and psychological medicine remain in separate silos. Utilising ACE research requires breaking down these long-standing divisions in healthcare between what is ‘physical’ and what is ‘mental’ or ‘emotional,’ and that’s hard to achieve. Physicians have been well-trained to deal only with what they can touch with their hands, see with their eyes, or view with microscopes or scans.
Just as physical wounds and bruises heal, just as we can regain our muscle tone, we can recover function in underconnected areas of the brain
However, now that we have scientific evidence that the brain is genetically modified by childhood experience, we can no longer draw that line in the sand. With hundreds of studies showing that childhood adversity hurts our mental and physical health, putting us at greater risk for learning disorders, cardiovascular disease, autoimmune disease, depression, obesity, suicide, substance abuse, failed relationships, violence, poor parenting and early death, we just can’t afford to make such distinctions.
Science tells us that biology does not have to be destiny. ACEs can last a lifetime, but they don’t have to. Just as physical wounds and bruises heal, just as we can regain our muscle tone, we can recover function in underconnected areas of the brain. If anything, that’s the most important take-away from ACE research: the brain and body are never static; they are always in the process of becoming and changing.
Even if we have been set on high-reactive mode for decades or a lifetime, we can still dial it down. We can respond to life’s inevitable stressors more appropriately and shift away from an overactive inflammatory response. We can become neurobiologically resilient. We can turn bad epigenetics into good epigenetics and rescue ourselves. We have the capacity, within ourselves, to create better health. We might call this brave undertaking ‘the neurobiology of awakening’.
Today, scientists recognise a range of promising approaches to help create new neurons (known as neurogenesis), make new synaptic connections between those neurons (known as synaptogenesis), promote new patterns of thoughts and reactions, bring underconnected areas of the brain back online – and reset our stress response so that we decrease the inflammation that makes us ill.

You can find ways to start right where you are, no matter how deep your scars or how long ago they occurred. Many mind-body therapies not only help you to calm your thoughts and increase your emotional and physical wellbeing, but research suggests that they have the potential to reverse, on a biological level, the harmful impact of childhood adversity.
Recent studies indicate that individuals who practice mindfulness meditation and mindfulness-based stress reduction (MBSR) show an increase in gray matter in parts of the brain associated with managing stress, and experience shifts in genes that regulate their stress response and their levels of inflammatory hormones. Other research suggests that a process known as neurofeedback can help to regrow connections in the brain that were lost to adverse childhood experiences.
Meditation, mindfulness, neurofeedback, cognitive therapy, EMDR (eye movement desensitisation and reprocessing) therapy: these promising new avenues to healing can be part of any patient’s recovery plan, if only healthcare practitioners would begin to treat the whole patient – past, present and future, without making distinctions between physical and mental health – and encourage patients to explore all the treatment options available to them. The more we learn about the toxic impact of early stress, the better equipped we are to counter its effects, and help to uncover new strategies and modalities to come back to who it is we really are, and who it was we might have been had we not encountered childhood adversity in the first place.


This is an adapted and reprinted extract from ‘Childhood Disrupted: How Your Biography Becomes Your Biology, and How You Can Heal’ (Atria), by Donna Jackson Nakazawa. Copyright © Donna Jackson Nakazawa, 2015.

White radish: 250g; scallion (including roots): 50g. Boil the two ingredients with 7cups of water to make a soup and drink 1 cup 3 times a day.
Scallion: 500 g; garlic: 250 g. Slice the ingredients into tiny bits and then add 2 liters of water, then boil.
Drink one teacup full, three times a day.

For educational purposes only This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

A study recently published in JAMA Neurology suggests that mothers with multiple sclerosis who breastfeed their babies exclusively during the first 2 months after giving birth could increase their chances of a 6-month reprieve from the disease.
A new study has found breastfeeding may have benefits for mothers with MS.Perceptions of multiple sclerosis (MS) have changed radically over the last 60 years. The National MS Society describe how, until 1950, women with MS were advised not to become pregnant, in the belief that the disease would worsen as a result.

On the contrary, the majority of research now not only shows that this is untrue, but it indicates a reduction in relapses during pregnancy, especially in the second and third trimesters, according to the Society.

Indeed, conception, pregnancy and delivery do not seem to be affected by MS. On the other hand, the chance of relapse in the first 6 months after giving birth is well documented.

During pregnancy, the body produces increased levels of corticosteroids as well as proteins that act as natural immunosuppressants. After giving birth, these natural benefits are reduced as hormones return to their pre-pregnancy levels - all of which contribute to a number of effects, including, for women with MS, a 20-30% chance of relapse within the first 3-4 months after delivery.

Now, new research suggests that exclusive breastfeeding for the first 2 months after giving birth could reduce the risk of relapse.

Exclusive breastfeeding reduced risk of MS relapseA team in Germany, led by Dr. Kerstin Hellwig of Rhur-University Bochum, surveyed 201 women over a 4-year period from 2008 to 2012.

The volunteers, who were registered with the German national MS and pregnancy registry, had expressed their intention either to breastfeed exclusively for 2 months after giving birth (59.7%), not to breastfeed or to breastfeed with regular supplementary feeds.

The findings showed that only 24.2% of the breastfeeding mothers suffered a relapse within the first 6 months after giving birth, in contrast with 38.3% of mothers who either did not breastfeed or did so only partially.

It seems that the mothers who breastfed their babies exclusively for the first 2 months increased their own chances of wellbeing for the first 6 months of motherhood.

Those who did not suffer a relapse at this time did seem to experience a return of symptoms in the second 6 months after giving birth, as they introduced supplemental feeding for their infants and as menstruation returned.

While commenting that the positive effect of breastfeeding "seems to be plausible," the authors of the report recommend that "women with MS should be supported if they choose to breastfeed exclusively," since at the very least, exclusive breastfeeding appears not to increase the chance of a relapse; indeed, they suggest that it may positively offer some relief from the disease at a time when new mothers most need it.

Dr. Hellwig told Medical News Today:

"I think these are very helpful and optimistic findings, as they clearly show that breastfeeding is not harmful [for MS patients]."

Limitations of the study include the fact that the participants had registered voluntarily, and that most of them had been using disease management treatments prior to becoming pregnant.

While breastfeeding is known to be beneficial for infants, a study recently reported by MNT found the practice may also expose infants to toxic chemicals known as perfluorinated alkylate substances (PFASs).

Written by Yvette Brazier
Reference: http://www.medicalnewstoday.com/articles/298961.php

For educational purposes only. This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

A chemical found in the Chinese herb known as Han Fang ji switches off the channels which the Ebola virus uses to enter and infect cells, according to research by US and German scientists. 

The scientists found that using a small dose of the chemical tetrandrine, but not the herb itself, stopped the virus from replicating and protected mice from the disease without obvious side effects.

The discovery of the promising drug therapy against Ebola is announced in the journal Science. 

Dr Robert Davey, of the Department of Immunology and Virology at Texas Biomedical Research Institute, says the small molecule Tetrandrine is a potent at inhibiting infection of human white blood cells in experiments and preventing Ebola virus disease in mice.

Scientists at Texas Biomed have been working in the Institute’s Biosafety Level 4 containment laboratory for more than 10 years to find a vaccine, therapies and detection methods for the Ebola virus.

The Ebola virus begins its entry into a cell by first binding to several types of cell surface proteins. Then the virus is taken into the cell and follows a route which transports the virus to cell compartments.

“When we tested in mice, the drugs stopped virus replication and saved most of them from disease,” Davey said.

This drug shows an ability to stop the virus before it has a chance interact with cells. 

“We are very excited about the progress made in this study and the momentum it provides as scientists across the world vigorously search for effective vaccines and treatments against Ebola virus,” Davey said. 

“We are cautiously optimistic. The next step in the process is to test both safety and effectiveness of the interaction of the drug with Ebola virus in non-human primates.”

So far 9,589 people have died in the West Africa Ebola outbreak, according to WHO (World Health Organisation).

Reference: http://www.businessinsider.com.au/a-chemical-within-a-traditional-chinese-medicine-has-been-found-to-be-effective-against-ebola-2015-2


For educational purposes only. This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.

In a stunning discovery that overturns decades of textbook teaching, researchers at the University of Virginia School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. That such vessels could have escaped detection when the lymphatic system has been so thoroughly mapped throughout the body is surprising on its own, but the true significance of the discovery lies in the effects it could have on the study and treatment of neurological diseases ranging from autism to Alzheimer's disease to multiple sclerosis.

"Instead of asking, 'How do we study the immune response of the brain?' 'Why do multiple sclerosis patients have the immune attacks?' now we can approach this mechanistically. Because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels," said Jonathan Kipnis, PhD, professor in the UVA Department of Neuroscience and director of UVA's Center for Brain Immunology and Glia (BIG). "It changes entirely the way we perceive the neuro-immune interaction. We always perceived it before as something esoteric that can't be studied. But now we can ask mechanistic questions."

"We believe that for every neurological disease that has an immune component to it, these vessels may play a major role," Kipnis said. "Hard to imagine that these vessels would not be involved in a [neurological] disease with an immune component."

New Discovery in Human Body
Kevin Lee, PhD, chairman of the UVA Department of Neuroscience, described his reaction to the discovery by Kipnis' lab: "The first time these guys showed me the basic result, I just said one sentence: 'They'll have to change the textbooks.' There has never been a lymphatic system for the central nervous system, and it was very clear from that first singular observation - and they've done many studies since then to bolster the finding - that it will fundamentally change the way people look at the central nervous system's relationship with the immune system."

Even Kipnis was skeptical initially. "I really did not believe there are structures in the body that we are not aware of. I thought the body was mapped," he said. "I thought that these discoveries ended somewhere around the middle of the last century. But apparently they have not."

'Very Well Hidden'
The discovery was made possible by the work of Antoine Louveau, PhD, a postdoctoral fellow in Kipnis' lab. The vessels were detected after Louveau developed a method to mount a mouse's meninges - the membranes covering the brain - on a single slide so that they could be examined as a whole. "It was fairly easy, actually," he said. "There was one trick: We fixed the meninges within the skullcap, so that the tissue is secured in its physiological condition, and then we dissected it. If we had done it the other way around, it wouldn't have worked."

After noticing vessel-like patterns in the distribution of immune cells on his slides, he tested for lymphatic vessels and there they were. The impossible existed. The soft-spoken Louveau recalled the moment: "I called Jony [Kipnis] to the microscope and I said, 'I think we have something.'"

As to how the brain's lymphatic vessels managed to escape notice all this time, Kipnis described them as "very well hidden" and noted that they follow a major blood vessel down into the sinuses, an area difficult to image. "It's so close to the blood vessel, you just miss it," he said. "If you don't know what you're after, you just miss it."

"Live imaging of these vessels was crucial to demonstrate their function, and it would not be possible without collaboration with Tajie Harris," Kipnis noted. Harris, a PhD, is an assistant professor of neuroscience and a member of the BIG center. Kipnis also saluted the "phenomenal" surgical skills of Igor Smirnov, a research associate in the Kipnis lab whose work was critical to the imaging success of the study.

Alzheimer's, Autism, MS and Beyond
The unexpected presence of the lymphatic vessels raises a tremendous number of questions that now need answers, both about the workings of the brain and the diseases that plague it. For example, take Alzheimer's disease. "In Alzheimer's, there are accumulations of big protein chunks in the brain," Kipnis said. "We think they may be accumulating in the brain because they're not being efficiently removed by these vessels." He noted that the vessels look different with age, so the role they play in aging is another avenue to explore. And there's an enormous array of other neurological diseases, from autism to multiple sclerosis, that must be reconsidered in light of the presence of something science insisted did not exist.

The findings have been published online by the prestigious journal Nature and will appear in a forthcoming print edition.

 Explore further: Major discovery on spinal injury reveals unknown immune response
Source: http://medicalxpress.com/news/2015-06-link-brain-immune.html


For educational purposes only. This information has not been evaluated by the Food and Drug Administration. This information is not intended to diagnose, treat, cure, or prevent any disease.